Educational resource · Not a medical device · Infectious diseases review in progress · Does not replace clinical judgement

Streptococcus agalactiae — Group B Streptococcus (GBS)

Review by an infectious diseases specialist in progress · edited by a physician, AI-assisted writing · level of evidence computed from the source type · page as of 25 October 2026 · Methodology

Streptococcaceae · Gram-positive

Le SGB est la 1ère cause de sepsis néonatal grave. Chez l'adulte, il touche préférentiellement les diabétiques, immunodéprimés et personnes âgées. Les atteintes ostéo-articulaires sont fréquentes chez l'adulte. Toute bactériémie à SGB chez la femme enceinte est une urgence obstétricale.

Scope: dosing as described in the cited guidelines (French or international context, stated by the source), for adults with normal renal function unless stated on the line. No renal or hepatic, paediatric or pregnancy adjustment is provided systematically. These regimens have not been reviewed by any infectious-disease specialist to date.

Documented organ tropism

Organs where foci of Streptococcus agalactiae are described in the cited literature. The reported frequency is not an individual probability.

Organ	Tropism	Level of evidence	Sources	Spread route
Bones / Joints	High tropism	Evidence B	2	not recorded
Meninges	High tropism	Evidence A	1	not recorded
Lung (néonatal)	High tropism	Evidence B	1	not recorded
Skin	Moderate tropism	Evidence B	1	not recorded
Heart / Endocardium	Rare tropism	Evidence B	1	not recorded

Described portals of entry

• Urinary system / Bladder
• Skin

Spread routes recorded: 0 of 5 documented foci A focus without a route is not a focus without spread: the route is simply not recorded.

Associated syndromes

• Bacterial meningitis
• Urinary tract infection (UTI) (cystitis / pyelonephritis)
• Septic arthritis and osteomyelitis

Sources

• Farley MM et al. — A population-based assessment of invasive disease due to group B Streptococcus in nonpregnant adults (1993) — doi:10.1056/NEJM199306243282503
• Phares CR et al. — Active Bacterial Core Surveillance (JAMA) (2008) — doi:10.1001/jama.299.17.2056
• Edmond KM et al. — Group B streptococcal disease in infants aged younger than 3 months (2012) — doi:10.1016/S0140-6736(11)61651-6
• ACOG — Prevention of Group B Streptococcal Early-Onset Disease in Newborns: Committee Opinion No. 797 (Obstet Gynecol) (2020) — doi:10.1097/AOG.0000000000003668
• ESC Guidelines for the management of endocarditis (Delgado V et al.) (2023) — doi:10.1093/eurheartj/ehad193

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