Educational resource · Not a medical device · Infectious diseases review in progress · Does not replace clinical judgement
Review by an infectious diseases specialist in progress · edited by a physician, AI-assisted writing · level of evidence computed from the source type · page as of 30 October 2026 · Methodology
Bartonellaceae (anc. Brucellaceae) · Gram-negative
Zoonose chronique par contact avec ruminants (bovins, ovins, caprins) ou consommation de produits laitiers non pasteurisés. Maladie à DO (déclaration aux autorités sanitaires). Fièvre ondulante de Malte. ATB : doxycycline (duration not verified) + streptomycine (duration not verified), ou doxycycline + rifampicine (duration not verified) (OMS 2006) — see cited source. Monothérapie : rechutes 10-20 % sous doxycycline seule — bithérapie en règle. Risque de rechute si traitement incomplet.
Scope: dosing as described in the cited guidelines (French or international context, stated by the source), for adults with normal renal function unless stated on the line. No renal or hepatic, paediatric or pregnancy adjustment is provided systematically. These regimens have not been reviewed by any infectious-disease specialist to date.
| Organ | Tropism | Level of evidence | Sources | Spread route |
|---|---|---|---|---|
| Bones / Joints | High tropism | Evidence B | 2 | hematogenous |
| Heart / Endocardium | Moderate tropism | Evidence B | 2 | hematogenous |
| Liver / Bile duct | Moderate tropism | Evidence B | 2 | not recorded |
| Central nervous system | Rare tropism | Evidence B | 2 | not recorded |
| Eye — Uvéite brucellaire | Rare tropism | Evidence B | 1 | hematogenous |
Spread routes recorded: 3 of 5 documented foci A focus without a route is not a focus without spread: the route is simply not recorded.
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