Educational resource · Not a medical device · Infectious diseases review in progress · Does not replace clinical judgement

Mycoplasmoides pneumoniae (formerly Mycoplasma pneumoniae) — Mycoplasma pneumoniae

Review by an infectious diseases specialist in progress · edited by a physician, AI-assisted writing · level of evidence computed from the source type · page as of 30 October 2026 · Methodology

Mycoplasmoidaceae · Cell-wall-less bacterium (Gram stain not applicable)

Bactérie sans paroi : invisible au Gram, insensible à toutes les bêta-lactamines. À évoquer devant une pneumonie communautaire peu sévère à début progressif, toux sèche traînante, chez un sujet jeune ou en collectivité ; les manifestations extra-pulmonaires (cutanéo-muqueuses, neurologiques, hémolyse à agglutinines froides) peuvent dominer le tableau. Diagnostic par PCR sur prélèvement respiratoire, la sérologie étant tardive. Traitement : macrolide ou doxycycline (IDSA/ATS 2019) ; résistance aux macrolides décrite, très inégale selon les régions (Waites 2017).

Scope: dosing as described in the cited guidelines (French or international context, stated by the source), for adults with normal renal function unless stated on the line. No renal or hepatic, paediatric or pregnancy adjustment is provided systematically. These regimens have not been reviewed by any infectious-disease specialist to date.

Documented organ tropism

Organs where foci of Mycoplasmoides pneumoniae (formerly Mycoplasma pneumoniae) are described in the cited literature. The reported frequency is not an individual probability.

Organ	Tropism	Level of evidence	Sources	Spread route
Lung	High tropism	Evidence B	3	direct
Skin	Moderate tropism	Evidence C	1	not recorded
Central nervous system	Moderate tropism	Evidence C	1	not recorded
Heart / Endocardium (myocardite, péricardite)	Rare tropism	Evidence C	1	not recorded

Described portals of entry

• Lung

Spread routes recorded: 1 of 4 documented foci A focus without a route is not a focus without spread: the route is simply not recorded.

Associated syndromes

• Community-acquired pneumonia (CAP)

Sources

• Metlay JP et al. — Diagnosis and Treatment of Adults with Community-acquired Pneumonia: ATS/IDSA Clinical Practice Guideline (Am J Respir Crit Care Med) (2019) — doi:10.1164/rccm.201908-1581ST
• Waites KB et al. — Mycoplasma pneumoniae from the Respiratory Tract and Beyond (CMR) (2017) — doi:10.1128/CMR.00114-16
• Pereyre S, Goret J & Bébéar C — Mycoplasma pneumoniae: current knowledge on macrolide resistance and treatment (Front Microbiol) (2016) — doi:10.3389/fmicb.2016.00974

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