Educational resource · Not a medical device · Infectious diseases review in progress · Does not replace clinical judgement

Legionella pneumophila — Legionella

Review by an infectious diseases specialist in progress · edited by a physician, AI-assisted writing · level of evidence computed from the source type · page as of 30 October 2026 · Methodology

Legionellaceae · Gram-negative

Légionellose : pneumopathie intracellulaire sévère — recherche de l'Ag urinaire Legionella recommandée dans toute PAC sévère. Contage hydrique (tours aéroréfrigérantes, eau chaude, climatisation). Maladie à DO (déclaration aux autorités sanitaires). ATB : azithromycine ou fluoroquinolone (lévofloxacine) — bétalactamines INEFFICACES (bactérie intracellulaire). Pas de transmission interhumaine.

Scope: dosing as described in the cited guidelines (French or international context, stated by the source), for adults with normal renal function unless stated on the line. No renal or hepatic, paediatric or pregnancy adjustment is provided systematically. These regimens have not been reviewed by any infectious-disease specialist to date.

Documented organ tropism

Organs where foci of Legionella pneumophila are described in the cited literature. The reported frequency is not an individual probability.

Organ	Tropism	Level of evidence	Sources	Spread route
Lung	High tropism	Evidence B	2	direct
Kidney	Moderate tropism	Evidence C	1	not recorded
Central nervous system	Moderate tropism	Evidence C	1	not recorded
Heart / Endocardium	Rare tropism	Evidence C	1	not recorded

Described portals of entry

• Lung

Spread routes recorded: 1 of 4 documented foci A focus without a route is not a focus without spread: the route is simply not recorded.

Associated syndromes

• Community-acquired pneumonia (CAP)

Sources

• Mandell LA et al. — IDSA/ATS CAP Consensus Guidelines (CID) (2007) — doi:10.1086/511159
• Metlay JP et al. — Diagnosis and Treatment of Adults with Community-acquired Pneumonia: ATS/IDSA Clinical Practice Guideline (Am J Respir Crit Care Med) (2019) — doi:10.1164/rccm.201908-1581ST
• Cunha BA et al. — Legionnaires' disease (Lancet) (2016) — doi:10.1016/S0140-6736(15)60078-2

This page is the text version, generated at build time. The 3D anatomical atlas requires JavaScript.