Educational resource · Not a medical device · Infectious diseases review in progress · Does not replace clinical judgement
Review by an infectious diseases specialist in progress · edited by a physician, AI-assisted writing · level of evidence computed from the source type · page as of 29 October 2026 · Methodology
Aspergillaceae · Mould
Mycose filamenteuse invasive touchant quasi-exclusivement les immunodéprimés profonds (neutropénie, greffe de moelle, corticothérapie prolongée, anti-TNF). Galactomannane sérique : biomarqueur clé chez les hémato-oncologiques. TDM thoracique : signe du halo (nodule > 1 cm entouré de verre dépoli), caractéristique de l'angio-invasion, surtout chez le neutropénique (Patterson 2016). ATB : voriconazole en 1ère intention (IDSA 2016). Isavuconazole alternative.
Scope: dosing as described in the cited guidelines (French or international context, stated by the source), for adults with normal renal function unless stated on the line. No renal or hepatic, paediatric or pregnancy adjustment is provided systematically. These regimens have not been reviewed by any infectious-disease specialist to date.
| Organ | Tropism | Level of evidence | Sources | Spread route |
|---|---|---|---|---|
| Lung | High tropism | Evidence B | 1 | direct |
| Central nervous system | Moderate tropism | Evidence B | 1 | hematogenous |
| Eye | Rare tropism | Evidence B | 1 | not recorded |
| Heart / Endocardium | Rare tropism | Evidence B | 1 | not recorded |
Spread routes recorded: 2 of 4 documented foci A focus without a route is not a focus without spread: the route is simply not recorded.
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